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A number of laboratories and companies have developed serological tests , which detect antibodies produced by the body in response to infection.

On 22 June , UK health secretary Matt Hancock announced the country would conduct a new "spit test" for COVID on 14, key workers and their families in Southampton , having them spit in a pot, which was collected by Southampton University , with results expected within 48 hours.

Hancock said the test was easier than using swabs and could enable people to conduct it at home. Characteristic imaging features on chest radiographs and computed tomography CT of people who are symptomatic include asymmetric peripheral ground-glass opacities without pleural effusions.

Strategies for preventing transmission of the disease include maintaining overall good personal hygiene, washing hands, avoiding touching the eyes, nose, or mouth with unwashed hands, and coughing or sneezing into a tissue, and putting the tissue directly into a waste container.

Those who may already have the infection have been advised to wear a surgical mask in public. Many governments have restricted or advised against all non-essential travel to and from areas affected by the outbreak.

Misconceptions are circulating about how to prevent infection; for example, rinsing the nose and gargling with mouthwash are not effective. Hand washing is recommended to prevent the spread of the disease.

The CDC recommends that people wash hands often with soap and water for at least twenty seconds, especially after going to the toilet or when hands are visibly dirty; before eating; and after blowing one's nose, coughing, or sneezing.

This is because outside the human body, the virus is killed by household soap, which bursts its protective bubble. Social distancing also known as physical distancing includes infection control actions intended to slow the spread of disease by minimising close contact between individuals.

Methods include quarantines; travel restrictions; and the closing of schools, workplaces, stadiums, theatres, or shopping centres.

Individuals may apply social distancing methods by staying at home, limiting travel, avoiding crowded areas, using no-contact greetings, and physically distancing themselves from others.

The maximum gathering size recommended by U. Older adults and those with underlying medical conditions such as diabetes, heart disease, respiratory disease, hypertension , and compromised immune systems face increased risk of serious illness and complications and have been advised by the CDC to stay home as much as possible in areas of community outbreak.

In late March , the WHO and other health bodies began to replace the use of the term "social distancing" with "physical distancing", to clarify that the aim is to reduce physical contact while maintaining social connections, either virtually or at a distance.

The use of the term "social distancing" had led to implications that people should engage in complete social isolation , rather than encouraging them to stay in contact through alternative means.

The CDC and WHO recommend individuals wear non-medical face coverings in public settings where there is an increased risk of transmission and where social distancing measures are difficult to maintain.

Masks are also strongly recommended for those who may have been infected and those taking care of someone who may have the disease.

Self-isolation at home has been recommended for those diagnosed with COVID and those who suspect they have been infected. Health agencies have issued detailed instructions for proper self-isolation.

Many governments have mandated or recommended self-quarantine for entire populations. Surfaces may be decontaminated with a number of solutions within one minute of exposure to the disinfectant for a stainless steel surface , including 62—71 percent ethanol , 50— percent isopropanol , 0.

Other solutions, such as benzalkonium chloride and chlorhexidine gluconate , are less effective. The CDC recommends ventilation in public spaces to help clear out infectious aerosols , as well several others, including those regarding air filtration , [20] [] however doctors have been cautious about recommending air filtration due to the potentially very small size of virus particles.

Some filters are labelled to remove viruses to the 5-micron level, but there are fears that some virus particles may be even smaller.

Strategies in the control of an outbreak are screening, containment or suppression , and mitigation. Screening is done with a device such as a thermometer to detect the elevated body temperature associated with fevers caused by the coronavirus.

When it is no longer possible to contain the disease, efforts then move to the mitigation stage: measures are taken to slow the spread and mitigate its effects on the healthcare system and on society.

A combination of both containment and mitigation measures may be undertaken at the same time. Part of managing an infectious disease outbreak is trying to delay and decrease the epidemic peak, known as flattening the epidemic curve.

More drastic actions aimed at containing the outbreak were taken in China once the severity of the outbreak became apparent, such as quarantining entire cities and imposing strict travel bans.

South Korea introduced mass screening and localised quarantines and issued alerts on the movements of infected individuals.

Singapore provided financial support for those infected who quarantined themselves and imposed large fines for those who failed to do so.

Taiwan increased face mask production and penalised hoarding of medical supplies. Simulations for Great Britain and the United States show that mitigation slowing but not stopping epidemic spread and suppression reversing epidemic growth have major challenges.

Optimal mitigation policies might reduce peak healthcare demand by two-thirds and deaths by half, but still result in hundreds of thousands of deaths and overwhelmed health systems.

Suppression can be preferred but needs to be maintained for as long as the virus is circulating in the human population or until a vaccine becomes available , as transmission otherwise quickly rebounds when measures are relaxed.

Long-term intervention to suppress the pandemic has considerable social and economic costs. Contact tracing is an important method for health authorities to determine the source of infection and to prevent further transmission.

On 10 April , Google and Apple jointly announced an initiative for privacy-preserving contact tracing based on Bluetooth technology and cryptography.

Due to capacity limitations in the standard supply chains , some manufacturers are 3D printing healthcare material such as nasal swabs and ventilator parts.

NASA is seeking fast-track approval. Antiviral medications are under investigation for COVID, though none have yet been shown to be clearly effective on mortality in published randomised controlled trials.

Taking over-the-counter cold medications, [] drinking fluids, and resting may help alleviate symptoms. Other trials are investigating whether existing medications can be used effectively against COVID or the immune reaction to it.

A study of major hospitals in the U. There are several theories about when and where the very first case the so-called patient zero originated.

According to official Chinese sources, these early cases were mostly linked to the Huanan Seafood Wholesale Market , which also sold live animals.

On 30 December , a test report addressed to Wuhan Central Hospital, from company CapitalBio Medlab, stated that there was an erroneous positive result for SARS , causing a group of doctors at Wuhan Central Hospital to alert their colleagues and relevant hospital authorities of the result.

During the early stages of the outbreak, the number of cases doubled approximately every seven and a half days. On 31 January , Italy had its first confirmed cases, two tourists from China.

On 11 June , after 55 days without a locally transmitted case being officially reported, [] the city of Beijing reported a single COVID case, followed by two more cases on 12 June.

On 29 June , WHO warned that the spread of the virus is still accelerating as countries reopen their economies, although many countries have made progress in slowing down the spread.

As of 31 August , more than Due to the pandemic in Europe , many countries in the Schengen Area have restricted free movement and set up border controls.

By 26 March, 1. On 20 January, the Chinese National Health Commission confirmed human-to-human transmission of the virus.

A further series of measures were instituted by the authorities in late February to contain the COVID outbreak, including issuing health declarations for travellers and extending the Spring Festival holiday, [] travel restrictions, [] and closure of museums, universities and schools around the country.

After the outbreak entered its global phase in March, Chinese authorities took strict measures to prevent the virus from re-entering China from other countries.

For example, Beijing imposed a day mandatory quarantine for all international travelers entering the city. India ordered a nationwide lockdown for the entire population starting 24 March, [] with a phased unlock beginning 1 June.

Six cities account for around half of all reported cases in the country— Mumbai , Delhi , Ahmedabad , Chennai , Pune and Kolkata. As of May , India had the largest number of confirmed cases in Asia ; [] as of August , behind the United States and Brazil , India had the third highest number of confirmed cases in the world, [] with the number of total confirmed cases breaching the , mark on 19 May [] and 2,, confirmed cases on 6 August On 10 June, India's recoveries exceeded active cases for the first time.

Iran became a centre of the spread of the virus after China during February. It is also suggested that U.

The nation's health agency reported a significant increase in confirmed cases on 20 February, [] largely attributed to a gathering in Daegu of the Shincheonji Church of Jesus.

South Korea introduced what was considered the largest and best-organised programme in the world to screen the population for the virus, isolate any infected people, and trace and quarantine those who contacted them.

On 23 March, it was reported that South Korea had the lowest one-day case total in four weeks. Although it was originally thought the pandemic reached France on 24 January , when the first COVID case in Europe was confirmed in Bordeaux , it was later discovered that a person near Paris had tested positive for the virus on 27 December after retesting old samples.

On 22 February, the Council of Ministers announced a new decree-law to contain the outbreak, including quarantining more than 50, people from eleven different municipalities in northern Italy.

Suspension of work activities and sports events has already been ordered in those areas. On 4 March, the Italian government ordered the full closure of all schools and universities nationwide as Italy reached a hundred deaths.

A lockdown was imposed on 14 March Medical professionals and those who live in retirement homes have experienced especially high infection rates.

Sweden differed from most other European countries in that it mostly remained open. The Swedish strategy focused on measures that could be put in place over a longer period of time, based on the assumption that the virus would start spreading again after a shorter lockdown.

The nature of devolution in the United Kingdom meant that each of the four countries of the UK had its own response to COVID with different rules and restrictions at different times and the UK government, on behalf of England, moving more quickly to lift restrictions.

On 23 March, the prime minister announced tougher social distancing measures, banning gatherings of more than two people and restricting travel and outdoor activity to that deemed strictly necessary.

Unlike previous measures, these restrictions were enforceable by police through fines and dispersal of gatherings. Most businesses were ordered to close, with exceptions for those deemed "essential", including supermarkets, pharmacies, banks, hardware shops, petrol stations, and garages.

The death toll in the United Kingdom was nearly 29, of those who tested positive for the virus. Later, it was calculated at 32,, after taking the official death count for Scotland and Northern Ireland into account.

By 2 March there were 80 confirmed cases, half of them in California. Florida and New York had declared their first two cases and the state of Washington reported many suspected cases and the first death.

Vice President Mike Pence maintained that the threat of the virus spreading throughout the U. On 13 March, Trump declared a national emergency , which made federal funds available to respond to the crisis.

The Times said that prior to 29 April only deaths confirmed through testing were reported, but new criteria included probable cases and deaths. As of 17 May, the U.

The White House was criticised for downplaying the threat and controlling messaging, directing health officials and scientists to coordinate public statements with the office of Vice-President Pence.

The White House refused to use the report, and Trump said he felt the guidelines were too restrictive, commenting "I see the new normal being what it was three months ago.

I think we want to go back to where it was. By mid-May reports of new cases began to level off and most states began to open restaurants and other businesses, placing limits on the numbers of people allowed in at one time.

The head of the NIAID , Anthony Fauci , warned that if caution was not used the rate of infections could rebound and he was particularly concerned about opening the schools in the fall.

President Trump expressed disapproval of Fauci's statements, saying "To me it's not an acceptable answer, especially when it comes to schools.

On April 17, the highest number of cases and deaths was registered in Brazil , [] followed by Peru and Colombia in the number of confirmed cases.

On 13 May, it was reported that Latin America and the Caribbean had reported over , cases of infection with 23, deaths.

On 22 May, citing especially the rapid increase of infections in Brazil, the World Health Organisation declared that South America is presently the epicentre of the coronavirus pandemic.

On 20 May it was reported that Brazil had a record 1, deaths in a single day, for a total of almost 18, fatalities.

With a total number of almost , cases, Brazil became the country with the third-highest number of cases, following Russia and the United States.

President Jair Bolsonaro has created a great deal of controversy referring to the virus as a "little flu" and frequently speaking out against preventive measures such as lockdowns and quarantines.

His attitude towards the outbreak has so closely matched that of U. President Donald Trump he has been called the "Trump of the Tropics".

In June , the government of Brazil attempted to conceal the actual figures of the COVID active cases and deaths, as it stopped publishing the total number of infections and deaths.

The last official numbers reported about , infections and over 34, deaths. According to Michael Yao, WHO's head of emergency operations in Africa, early detection is vital because the continent's health systems "are already overwhelmed by many ongoing disease outbreaks".

Even in the best scenario, the United Nations says 74 million test kits and 30, ventilators will be needed by the continent's 1. The mortality rates of COVID cases in African countries are relatively low compared to Europe due to the younger age of their populations.

Cases have been confirmed in all African countries, with Lesotho the last country to report its first coronavirus case on 13 May On 19 May , Australia filed a motion with the UN for an inquiry into the origins of the virus, and the response of the UN and governments.

More than countries supported this motion, and it was passed unanimously. As a result of the pandemic, many countries and regions imposed quarantines, entry bans, or other restrictions, either for citizens, recent travellers to affected areas, [] or for all travellers.

Concerns have been raised over the effectiveness of travel restrictions to contain the spread of COVID The European Union rejected the idea of suspending the Schengen free travel zone and introducing border controls with Italy, [] [] a decision which has been criticised by some European politicians.

Owing to the effective quarantine of public transport in Wuhan and Hubei, several countries evacuated their citizens and diplomatic staff from the area, primarily through chartered flights of the home nation, with Chinese authorities providing clearance.

On 15 February, the U. The United Nations has coordinated the global response to the coronavirus pandemic, led by its Secretary-General.

The response can be divided into formal resolutions at the General Assembly and at the Security Council UNSC , and operations via its specialized agencies , chiefly the World Health Organization in the initial stages, but involving more humanitarian-oriented agencies, like UNICEF , [] the International Labour Organization , [] and the Office of the United Nations High Commissioner for Human Rights [] as the humanitarian impact became clearer, and then economic organizations, like the United Nations Conference on Trade and Development , [] the International Monetary Fund , [] and the World Bank , [] as the socioeconomic implications worsened.

Taiwan posted an inquiry to the WHO on 31 December On 30 January, the WHO declared the outbreak a Public Health Emergency of International Concern PHEIC , warning that "all countries should be prepared for containment, including active surveillance, early detection, isolation, and case management, contact tracing and prevention of onward spread" of the virus, [7] [] following an increase in cases outside China.

This was the sixth-ever PHEIC since the measure was first invoked during the swine flu pandemic. The outbreak is a major destabilising threat to the global economy.

Agathe Demarais of the Economist Intelligence Unit has forecast that markets will remain volatile until a clearer image emerges on potential outcomes.

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